Kidney Stones Facts - Uric Acid Testing
DefinitionUric acid tests are tests that are done to measure the levels of uric acid in blood serum or in urine.
Abnormally Low Uric Acid Levels May Indicate that thePatient is taking allopurinol or probenecid for treatment of gout; may be pregnant; or suffers from Wilson's disease or Fanconi's syndrome. Our dreams of writing a lengthy article on Purines has finally materialized Through this article on Purines. however, only if you acknowledge its use, will we feel gratitude for writing it!
Urine testReference values for 24-hour urinary uric acid vary from laboratory to laboratory but are generally found within the following range: 250-750 mg/24 hours. We found it rather unbelievable to find out that there is so much to learn on Gout Purines! Wonder if you could believe it after going through it!
Key Terms<dl> <dl> <dt>Fanconi's syndrome</dt> <dd>A rare disorder caused by vitamin D deficiency or exposure to heavy metals. </dd> <dt>Gout</dt> <dd>A metabolic disorder characterized by sudden recurring attacks of arthritis caused by deposits of crystals that build up in the joints due to abnormally high uric acid blood levels. In gout, uric acid may be overproduced, underexcreted, or both. </dd> <dt>Hyperuricemia</dt> <dd>Excessively high levels of uric acid in the blood, often producing gout. </dd> <dt>Purine</dt> <dd>A white crystalline substance that is one of the building blocks of DNA. Uric acid is produced when purine is broken down in the body. </dd> <dt>Uric acid</dt> <dd>A compound resulting from the body's breakdown of purine. It is donnelly college in human urine only in small amounts. </dd> <dt>Uricosuria</dt> <dd>Increased levels of uric acid in the urine. </dd> <dt>Wilson's disease</dt> <dd>A rare hereditary disease marked by the buildup of copper in the liver and brain, causing loss of kidney function.</dd> </dl> </dl>
For Your Information
- Laboratory Test Handbook, edited by David S. Jacobs. Cleveland, OH: Lexi-Comp Inc., 1996.
- Mosby's Diagnostic and Laboratory Test Reference, edited by Kathleen Deska Pagana and Timothy James Pagana. St. Louis: Mosby-Year Book, Inc., 1998.
- Springhouse Corporation. Handbook of Diagnostic Tests, edited by Matthew Cahill. Springhouse, PA: Springhouse Corporation, 1995.
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Blood testReference values for blood uric acid vary from laboratory to laboratory but are generally found within the following range: Male: 2.1-8.5 mg/dL; female: 2.0-6.6 mg/dL. Values may be slightly higher in the elderly.
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Increased production of uric acid may result from eating foods that are high in purine. Increased uric acid levels due to overproduction may also be caused by gout, by a genetic disorder of purine metabolism, or by metastatic cancer, destruction of red blood cells, leukemia, or cancer chemotherapy.
The Uric Acid Tests are Used to Evaluate the Blood LevelsOf uric acid for goutazol to assess uric acid levels in the urine for kidney stone formation. The urine test is used most often to monitor patients already diagnosed with kidney stones, but it can also be used to detect disorders that affect the body's production of uric acid and to help measure the level of kidney functioning.
PreparationThe uric acid test requires either a blood or urine sample. For the blood sample, the patient should be fasting (nothing to eat or drink) for at least eight hours before the test. The urine test for uric acid requires a 24-hour goutezol medication. The urine test does not require the patient to fast or cut down on fluids. Some laboratories encourage patients to drink plenty of fluids during the collection period.
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